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What maternal condition may contribute to the risk of an ectopic pregnancy?

  1. Pregnancy in the first trimester

  2. History of pelvic inflammatory disease

  3. History of multiple births

  4. Normal menstrual cycles

The correct answer is: History of pelvic inflammatory disease

A history of pelvic inflammatory disease is a well-established risk factor for ectopic pregnancy. Pelvic inflammatory disease (PID) often results from sexually transmitted infections or other infections that affect the reproductive organs. The inflammation and damage caused by these infections can lead to the formation of scar tissue and adhesions in the fallopian tubes. This can disrupt the normal transport of the fertilized egg from the ovary to the uterus, causing it to implant in the fallopian tube instead of the uterine cavity, which characterizes an ectopic pregnancy. In contrast, the other options do not significantly contribute to the risk of ectopic pregnancy. Pregnancy in the first trimester is a normal stage of pregnancy and does not inherently increase the risk of having an ectopic pregnancy. A history of multiple births might suggest previous pregnancies but does not have a direct correlation with the risk of ectopic implantation. Normal menstrual cycles are indicative of regular ovulation and uterine health but do not contribute to the likelihood of ectopic pregnancies either.